HYPOCHROMIC ANAEMIA::
Hypochromic anaemia is due to reduced amount of Hb in the RBC This indicates defective Hb formation and hence deficiency of iron it is thus described as iron deficiency anaemia the RBCs are generally of smaller size (<7.2u) and so it is also known as microcytic anaemia the person suffering from this type of anaemia must be advised to take more leafy vegetables green leaves fruits liver meat etc because these are good sources of iron if necessary then iron preparation containing ferrous fumarate should be given iron is absorbed easily by the gastrointestinal tract in the ferrous form
Hyperchromic anaemia is due to defective RBC formation the Hb% may be normal but total RBC count is less size of RBC is usually large (macrocytic anaemia) because its maturation does not take place the cells are megaloblasts and hence this type of anaemia is described as megaloblastic anaemia the cause is deficiency of vit B12 (cyanocobalamine ) and so it is also known as vit B12 deficiency anaemia or pernicious anaemia
vit B12 is the only vitamin known to require a specific secretion from the pylorus of stomach to facilitate its absorption this is the intrinsic factor of castle vit B12 extrinisic factor deficiency is usually not associated with defective diet but defective absorption of vit B12 thus for treatment of this type of anaemia vit B12 must be combined with intrinsic factor of castle vit B12 is stored mainly in the liver and it is the best source of vit B12 other poor sources are milk and butter vit B12 can never be synthesized by plants it is usually synthesized by microbes which may be present in the gastrointestinal tract of animals
the importance of vit B12 is its inter relationship with folic acid folic acid is another water soluble vitamin of vit B complex chemically it is pteroylglutamic acid it is necessary for normal growth of nerve fibres both vitamins are interrelated to each other the haemotological damage may be corrected by folic acid but will not correct neurological damage due to vit B12 deficiency
0 Comments