Non-specific cellular and chemical defenses
summary of nonpecific body defense mechanisms ::
THE DEFENCE SYSTEMS OF THE BODY The defensive mechanism is an inborn instinct of a l…
PROSTACYLINS THROMBOXANE AND LEUKOTRIENES These substances have been recently discove…
Miscellaneous Actions:: PGE1 and PGD2 are potent inhibitors of platelet aggregation s…
Pharmacological Action:: Prostaglandins produce variety of effects and different types…
NEUROPEPTIDE Y AND NEUROTENSIN Neuropeptide-Y is a 36 aminoacid peptide found in hig…
Pharmacological action of ANF are as follows:: 1.it causes increase in sodium excreti…
VASOPRESSIN It is a posterior pituitary hormone that cause antidiuretic action (henc…
KININOGENS:: Kininogens are the precursors of kinins they are present in plasma lymph…
Structure and function of peptide mediators:: Size varies from three to several hundr…
BIOSYNTHESIS AND REGULATION OF PEPTIDES Peptide structure is directly coded in the g…
Purines as mediators ATP functions as a neurotransmitter (or co-transmitter) at perip…
Purines as mediators:: ATP funcation as a neurotransmitter (or co-transmitter) at per…
Central Nervous System::: 5-HT is normally found in the brain (1%) and its deficienc…
Physiological Actions:: Gastrointestinal Tract: Serotonin stimulates i…
PRECURSR Precursor in the biosynthesis of 5-HT is tryptophan it is converted to 5-hyd…
5-HYDROXYTRYPTAMINE (5-HT)
5- HT Receptor classification :: Recently various subtypes of 5-HT receptors have been…
Histamine receptors:: Two types of histamine receptors have been identified :(1) H1 r…
Triple response in skin:: Local application of histamine on skin produces a typical re…
Gastric acid secretion :: The secretion of gastric juice is promptly stimula…
Physiological actions of histamine:: smooth muscles:: The smooth muscles are stimulate…
Chemistry synthesis and fate of histamine:: Chemically histamine is 5-(2- aminoethyl)…
HISTAMINE Histamine is the first vasoactive amine to be identified in the bod…
AUTACOIDS:: Autacoids are those naturally occurring substances that produce astonishi…
DISORDERS OF LYMPH AND LYMPHATIC SYSTEM Oedema:: It is a condition which represents …
Functions of Spleen:: 1. Formation of blood cells:: (a) RBCs are formed by the spleen…
Structure of spleen: Spleen is a lymphoid organ covered with an elastic fibrous capsu…
Functions of Lymph Nodes:: They form the first line of defence like the soldiers guar…
Factors Affecting Lymph Circulation:: Lymph flows in a closed system of lymphatic ves…
CIRCULATION OF LYMPH AND LYMPHATIC SYSTEM:: Lymph flows in a closed system of vessels…
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