DRUG INTERACTIONS :: When two or more drugs are taken at the same time there is a pos…
SYNERGISM :: If two or more drugs are taken simultaneously they increase the potency…
TACHYPHYLAXIS :: Tachyphylaxis is defined as an acute type of tolerance in other word…
TOLERANCE :: On repeated dosage if more drug is required by the patient than the usua…
CUMULATION :: When the intake of drug exceeds clearance the continuous administration…
GENETIC FACTORS :: The effect of drug may be altered by influence of heridity The bra…
FACTORS AFFECTING ACTION OF DRUGS :: Physiological State of Mind :: The mind affects t…
FACTORS AFFECTING ABSORPTION OF DRUG :: (A) Factors affecting dissolution rate -high t…
SEX :: Females require 0.85 of the male dose partly because of their lesser weight an…
DOSAGE CALCULATIONS :: Rules for Infants and children s doses :: 1.Young s Rule (for…
FACTORS AFFECTING BIOAVAILABILITY AND ACTION OF DRUGS :: There are number of factors …
SIGNIFICANCE OF BIOEQUIVALENCE :: (1) It is a better and an alternate method for the …
COMPARATIVE BIOAVAILABILITY AND BIOEQUIVALENCE :: The measurement of plasma concentr…
SIGNIFICANCE OF BIOAVAILABILITY :: The term bioavailability was intraduced by Oster (…
CLEARANCE :: It is one of the most important concept of pharmacokinetics useful for d…
TABLET DISINTEGRATION TIME :: It is the time required for a tablet to disintergrate w…
MULTIPLE DOSE BIOAVAILABILITY :: If the drug is administered in repeated does then the…
SINGLE DOSE BIOAVAILABILITY :: The most reliable and sensitive method for the determi…
BIOAVAILABILITY :: Bioavailability is the term used to describe the proportion of the…
IMPACT OF MOLECULAR PHARMACOLOGY IN UNDERSTANDING MECHANISMS AND DEVELOPMENT OF NEW D…
MOLECULAR PHARMACOLOGY If one looks into the history of pharmacology it becomes appa…
Some examples of Enzymes as Drug Targets :: Name of the Enzyme …
SOME EXAMPLES OF ION - CHANNELS AS DRUG TARGETS :: Ion channel …
TYPE IV:: GENE TRANSCRIPTION REGULATORY RECEPTORS OR NUCLEAR RECEPTORS :: Like k…
transduction mechanism of kinase linked receptors The first step following agonist bl…
TYPE II : G-PROTEIN COUPLED RECEPTORS :: These are membrane receptors coupled to G-pr…
MOLECULAR CLASSIFICATION OF RECEPTORS :: Based on molecular structure signal transduc…
REGULATION OF DNA TRANSCRIPTION AND HENCE OF PROTEIN SYNTHESIS :: This type of recept…
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