OSMOTIC DIURETICS
OSMOTIC DIURETICS :: The substances after passing through the glomeruli are not reabs…
CARDIAC GLYCOSIDES ::
CARDIAC GLYCOSIDES :: They increase the output of urine which may be due to increased…
CLASSIFICATION OF DIURETICS ACCORDING TO POTENCY ::
CLASSIFICATION OF DIURETICS ACCORDING TO POTENCY :: A.Weak diuretics :: 1.osmotic diu…
CLASSIFICATION OF DIURETICS ACCORDING TO SITE OF ACTION
CLASSIFICATION OF DIURETICS ACCORDING TO SITE OF ACTION :: 1.Drugs increasing renal s…
IN PROXIMAL TUBULE THERE OCCURS
IN PROXIMAL TUBULE THERE OCCURS :: (1) Active absorption of 60% of filtered Na+ (2) A…
DIURETICS
DIURETICS :: Elimination of larger amounts of urine than normal is called diuresis an…
ORAL GLYCOPROTEIN IIb/IIIa ANTAGONISTS
ORAL GLYCOPROTEIN IIb/IIIa ANTAGONISTS :: The development of prodrugs with RGD sp…
BIOLOGICAL AND PLASMA HALF LIFE PROFILES
BIOLOGICAL AND PLASMA HALF LIFE PROFILES :: This affects the duration of inhibition o…
PHARMACOLOGICAL PROPERTIES OF GP IIb/IIIa Receptor antagonists
PHARMACOLOGICAL PROPERTIES OF GP IIb/IIIa Receptor antagonists :: A summary of pharma…
GP IIb/IIIa Receptor Antagonists Part 2
GP IIb/IIIa Receptor Antagonists Part 2 :: The first GP IIb/IIIa antagonist developed…
GP IIb/IIIa Receptor Antagonists
GP IIb/IIIa Receptor Antagonists :: Natural products were initially been screened …
TISSUE- PLASMINOGEN ACTIVATOR OR RTPA OR ALTEPLASE
TISSUE- PLASMINOGEN ACTIVATOR OR RTPA OR ALTEPLASE :: This has remarkable specificity…
FIBRINOLYTIC AGENTS
FIBRINOLYTIC AGENTS :: Fibrinolytic agents are those which prevent the formation of f…
DIPYRIDAMOLE AND SULFINPYRAZONE
DIPYRIDAMOLE AND SULFINPYRAZONE :: Competitively and reversibly inhibits the enzyme p…
ASPIRIN
ASPIRIN:: It inactivates irreversibly cyclo-oxygenase in platelets and in vascular en…
PHARMACOTHERAPY OF ACS PART 3
PHARMACOTHERAPY OF ACS PART 3 :: Newer agents like ticlopidine and clopidogrel were…
PHARMACOTHERAPY OF ACS PART 2
PHARMACOTHERAPY OF ACS PART 2 :: Aspirin however blocks only one of the several signa…
PHARMACOTHERAPY OF ACS
PHARMACOTHERAPY OF ACS :: Given the key role of thrombosis pharmacologic therapy has …
PLATELET AGGREGATION
PLATELET AGGREGATION :: Activation of platelets finally results into platelet aggrega…
PLATELET ACTIVATION
PLATELET ACTIVATION :: Local mechanical or biochemical stimuli can induce activation …
PLATELET ADHESION
PLATELET ADHESION :: Damage to the vessel wall and local exposure of the subendotheli…
PATHOPHYSIOLOGY OF ACS
PATHOPHYSIOLOGY OF ACS :: Key step in the formation of occlusive platelet -rich throm…
KHELLIN
KHELLIN :: It is found in fruits and seeds of the Egyptain plant Ammi visanaga it pro…
NICOTINIC ACID AND NICOTINYL ALCOHOL
NICOTINIC ACID AND NICOTINYL ALCOHOL :: These agents are weak coronary vasodilators b…
OTHER CORONARY DILATORS
Papaverine :: It is an alkaloid obtained from opium it causes relaxation of the smoot…
PHARMACOKINETICS AND DOSAGE
PHARMACOKINETICS AND DOSAGE :: Amylnitrite is rapidly absorbed from the lungs and oth…
MOLECULAR MECHANISM OF ACTION OF NITRITIES
One therapeutic application of the otherwise toxic effect of nitrite has been in cya…
PHARMACOLOGICAL ACTION
PHARMACOLOGICAL ACTION :: Nitrites are potent coronary vasodilators By dilatation of …
NITRITES
NITRITES :: These agents are simple nitric and nitrous acid esters of polyalcohols Th…
ACUTE CORONARY SYNDROMES (ACS)
ACUTE CORONARY SYNDROMES (ACS) :: Acute coronary syndromes (ACS) were recognized as e…
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